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Symbol
Name
ID
Rxra
retinoid X receptor alpha
MGI:98214
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations
Human Phenotypes
Lymphadenopathy
Hepatosplenomegaly
Disease(s) Associated with RXRA
pancreatic cancer

Mouse Phenotypes
abnormal cardiovascular system morphology
abnormal pharyngeal arch artery morphology
aortopulmonary window
pulmonary artery stenosis
abnormal vasculogenesis
abnormal myocardium layer morphology
abnormal myocardial fiber morphology
myocardial fiber degeneration
abnormal myocardial trabeculae morphology
trabecula carnea hypoplasia
abnormal myocardium compact layer morphology
ventricular myocardium compact layer hypoplasia
abnormal ventricle papillary muscle morphology
abnormal conotruncal ridge morphology
abnormal truncus arteriosus septation
persistent truncus arteriosus
abnormal heart development
abnormal atrioventricular cushion morphology
failure of atrioventricular cushion closure
abnormal conotruncus septation
abnormal heart morphology
double outlet right ventricle
abnormal atrioventricular valve morphology
abnormal mitral valve morphology
mitral valve atresia
mitral valve stenosis
abnormal tricuspid valve morphology
abnormal heart left atrium morphology
dilated heart right atrium
complete atrioventricular septal defect
abnormal interventricular septum morphology
muscular ventricular septal defect
abnormal heart ventricle shape
enlarged heart
ventricular hypoplasia
abnormal heart ventricle morphology
decreased heart left ventricle wall thickness
decreased heart right ventricle wall thickness
thin ventricular wall
dilated heart right ventricle
abnormal pericardial cavity morphology
abnormal pericardium morphology
dilated cardiomyopathy
decreased cardiac output
decreased ventricle muscle contractility
decreased heart rate
atrioventricular block
heart block
congestive heart failure
Availability Mouse Genotype
Rxratm1.1Krc/Rxratm1.1Krc
Rxratm1.1Pcn/Rxratm1.1Pcn
Rxratm1Ipc/Rxratm1Ipc
Rxratm1Rev/Rxratm1Rev
Rxratm2Ipc/Rxratm2Ipc
Rxratm3Ipc/Rxratm3Ipc
Rxratm4.1Ipc/Rxratm4.1Ipc
Rxratm1Rev/Rxra+
Rxratm2Ipc/Rxratm4.1Ipc
Tg(Myh6-Rxra)41Pcn/0
Rxratm1Ipc/Rxratm1Ipc
Tg(Myh6-Rxra)41Pcn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory